Plasma Filler (Biofiller)

Plasma Filler in Derby

Plasma Filler (Biofiller): A Natural Regenerative Approach to Facial Rejuvenation

Plasma Filler, also known as Biofiller, is an advanced regenerative aesthetic treatment that uses the patient’s own blood-derived plasma to restore volume, improve skin quality, and stimulate collagen production. Unlike synthetic dermal fillers, plasma filler is 100% autologous, making it a natural option for patients seeking subtle, biocompatible rejuvenation.

This innovative treatment bridges the gap between PRP (Platelet-Rich Plasma) and traditional fillers, offering both regenerative benefits and structural support.

What Is Plasma Filler / Biofiller?

Plasma filler is created by processing a small sample of the patient’s blood to isolate plasma rich in growth factors. Through a controlled heating and cooling process, the plasma transforms into a gel-like substance that can be injected to restore volume and improve skin texture.

Because it is derived from the patient’s own blood, plasma filler integrates naturally with the tissue and supports long-term skin regeneration.

Plasma filler offers a unique, natural alternative for patients seeking subtle volume restoration and skin rejuvenation without synthetic fillers. By harnessing the body’s own regenerative potential, this treatment supports healthier, more youthful-looking skin from within.

For personalised advice and to determine whether plasma filler is right for you, we recommend booking a consultation with our medical aesthetics team.

BOOK NOW

Key Benefits of Plasma Filler

  • 100% natural and biocompatible (no synthetic substances)
  • Restores soft, natural-looking volume
  • Stimulates collagen and elastin production
  • Improves skin texture, tone, and elasticity
  • Lower risk of allergic reactions or rejection
  • Suitable for patients who prefer non-synthetic treatments
  • Gradual, subtle rejuvenation with a natural finish

Common treatment areas

Common treatment areas include:

  • Under-eye hollows (tear troughs)
  • Cheeks and mid-face
  • Nasolabial folds
  • Marionette lines
  • Jawline and pre-jowl sulcus
  • Hands

Contraindications

Plasma filler is generally safe, but it may not be suitable for everyone. Contraindications include:

  • Active skin infections or inflammation at the treatment site
  • Blood disorders or clotting abnormalities
  • Autoimmune diseases (relative contraindication)
  • Severe anemia
  • Active cancer or ongoing chemotherapy
  • Use of anticoagulant therapy (assessment required)

A full medical consultation is essential to determine suitability.

Possible Side Effects

As plasma filler is derived from the patient’s own blood, side effects are usually mild and temporary. These may include:

  • Redness or swelling at injection sites
  • Mild bruising
  • Tenderness or discomfort
  • Temporary lumpiness or firmness
  • Rare risk of infection

Most side effects resolve within a few days, and downtime is minimal.

Frequently Asked Questions (FAQ)

Results typically last 6–12 months, depending on metabolism, treatment area, and lifestyle factors. The results will be visible after one session however for best resulst that will last up to 2 years we recommend 3 session with 2 months gap in between.

No. While both use your own blood, plasma filler is processed into a gel for volume restoration, whereas PRP is primarily used for skin quality and regeneration without adding volume.

Discomfort is minimal. A topical numbing cream is usually applied, and the procedure is well tolerated.

Approximately 30  minutes, including blood collection and processing.

You may notice immediate volume improvement, with continued skin enhancement over the following weeks as collagen production increases.

Yes. Plasma filler can be safely combined with treatments such as PRP, microneedling, skin boosters, or energy-based devices for enhanced results.